From a nutritional perspective, synergism is the way certain nutrients within a food are interlinked and work together as a team. The fact that iron is absorbed better in the presence of vitamin C is a very simple example of synergism, but if I pick up my Nutrition Bible, the synergistic nutrients listed for iron are Vit B2, B12, citrate, copper, clic acid, histidine, lysine, molybdenum, and selenium.

In this, one of my favourite textbooks by Henry Osieki, Henry describes synergistic nutrients as those who “work together in particular metabolic pathways as well as cofactors that activate the nutrient in question.” He says that “supplementing a synergistic combination of nutrients with the nutrient in question will result in better health outcomes at (a)lower dose of the star nutrient for a condition.” Continue reading