There seems to be an awful lot of carry on about methylcobalamin vs cynanocobalamin, but lots of mixed opinions. If someone is trying to sell you methylcobalamin, you can be certain they will demonise cyanocobalamin and scare you by using the word “Cyanide!!”, but is it really that simple?
Here are some of the various perspectives:
*Cyanocobalamin is safer because this is what all the research so far has been done on. We don’t know enough about methylcobalamin yet to safely supplement it or to know what dose is appropriate (which is why you will find such widely varying opinions about dose).
*Methylcobalamin is a waste of money. A Dr Greger quote : “Vitamin B12 supplements are so cheap to produce that supplement manufacturers try to come with all sorts of fancy ways to “add value” to products so they can make more money.”
*It doesn’t matter which one you use, as long as you use one.
*Cyanocobalimin is artificially produced (not found in nature in any significant quantity) and our body has to methylate it to turn it into methlycobalamin anyway, so why not just use methylcobalamin, a form more naturally found in nature anyway?
*Cyanocobalamin contains cyanide, but keep in mind this is a naturally occurring chemical in many foods anyway and it’s only present in B12 in very tiny amounts. Even at 1000µg dose, the cyanide in cyanocobalamin is 140x less than 2 tablespoons of flax seeds.
*Some say that cyanocobalamin is perfectly fine so long as you are a good methylater, a non-smoker and don’t have kidney failure.
*The methylcobalamin form of B12 is not as well absorbed and assimilated in the body. Scientists refer to this as being ‘unstable’. As such, the recommended B12 dosage for methylcobalamin is much higher than that of cyanocobalamin. Jack Norris (vegan dietician) recommends 1000 to 2000 mcg per day. Dr Greger, recommends 2000 mcg of methylcobalamin B12 daily. But both of them think cyanocobalimin is perfectly fine for most people.